NCT01053234

Different Insulin Regimens and Postprandial Coagulation Activation

Effects of Standardised Meals on Postprandial Coagulation Activation in Patients With Type 2 Diabetes Treated With Two Different Insulin Regimens

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 78 (actual)
• Sponsor: Esbjerg Hospital - University Hospital of Southern Denmark · Academic / Other
• Sex: All
• Age: 30 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study in patients with type 2 diabetes was to investigate the acute effect of postprandial blood glucose levels modified by two different insulin treatment regimens on coagulation activation, inflammation and endothelial cell function. The investigators hypothesized that the rapid-acting insulin analogue aspart has a beneficial postprandial effect on coagulation, endothelial dysfunction and inflammation compared with the intermediate-acting insulin NPH due to its ability to lower postprandial glycaemia.

Conditions

• Type 2 Diabetes
• Cardiovascular Risk
• Hemostasis
• Inflammation
• Endothelial Function

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Standardised meals

Timeline

• Start date: 2007-02-01
• Primary completion: 2007-05-01
• Completion: 2007-05-01
• First posted: 2010-01-21
• Last updated: 2022-10-19

Locations

1 site across 1 country: Denmark