NCT01052597

Curcumin for Type 2 Diabetic Patients

Antiatherogenic and Antimetabolic Effect of Curcumin in Type 2 Diabetic Patients

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Srinakharinwirot University · Academic / Other
• Sex: All
• Age: 35 Years
• Healthy volunteers: Not accepted

Summary

There are evidence that there is an association between insulin resistance and prolonged hyperinsulinemia or hyperglycemia in Type 2 diabetic patients. This will trigger oxidative stress system via reactive oxygen species (ROS) and lead to a high level of Nitric oxide. This can contribute to a significant change in blood vessel and could end up with the complications from cardiovascular disease and increased mortality rate of type 2 diabetic patients. The purpose of the present study was to examine the effectiveness of the curcumin in type 2 diabetic patients on the reduction of atherosclerosis events by examining pulse-wave velocity (PWV) and plasma high-sensitivity C-reactive protein (CRP) test and on blood sugar lowering, glycosylated hemoglobin (HBA1c), lipid profile, and insulin resistance.

Conditions

• Type 2 Diabetes Mellitus
• Cardiovascular Abnormalities

Interventions

Type	Name	Description
DRUG	curcumin	Curcumin capsule contains 250 mg curcuminoids, 2 capsule per time, 3 times a day for 12 months

Timeline

• Start date: 2009-07-01
• Primary completion: 2010-02-01
• Completion: 2010-03-01
• First posted: 2010-01-20
• Last updated: 2010-01-20

Locations

1 site across 1 country: Thailand