NCT01050517

Safety and Efficacy of Drug Combinations Against Triple Infections

Gaps in Helminth Control: Safety and Efficacy of Drug Combinations Against Triple Infections

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 250 (estimated)
• Sponsor: DBL -Institute for Health Research and Development · Academic / Other
• Sex: All
• Age: 5 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

This randomised, controlled, double blinded clinical study investigates the safety and efficacy of the combination of albendazole, ivermectin and praziquantel in the treatment of children aged 5-18 years co-infected with lymphatic filariasis, schistosomiasis and soil-transmitted helminthiasis.

Conditions

• Parasitic Diseases

Interventions

Type	Name	Description
DRUG	albendazole + ivermectin + praziquantel	albendazole (400 mg one dose) + ivermectin 200 microgram/kg body weight) + praziquantel (40 mg/kg)
DRUG	albendazole + ivermectin + (1 week later) praziquantel	albendazole (400 mg one dose) + ivermectin (200 microgram/kg body weight) + (1 week later) praziquantel (40 mg/kg)

Timeline

• Start date: 2007-10-01
• Primary completion: 2007-12-01
• Completion: 2007-12-01
• First posted: 2010-01-15
• Last updated: 2010-01-15

Locations

1 site across 1 country: Uganda