NCT01050452

Safety and Efficacy of Drug Combinations Against Trichuris Trichiura

Gaps in Helminth Control: Safety and Efficacy of Drug Combinations. Study on Trichuris Trichiura.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 750 (estimated)
• Sponsor: DBL -Institute for Health Research and Development · Academic / Other
• Sex: All
• Age: 5 Years – 15 Years
• Healthy volunteers: Not accepted

Summary

This randomised, controlled, double-blinded clinical study investigates the safety and efficacy of albendazole (ALB), mebendazole (MBD) and ivermectin (IVM) separately, and ALB and MBD each in combination with IVM in the treatment of Trichuris trichiura in children aged 5-14 years.

Conditions

• Parasitic Diseases

Interventions

Type	Name	Description
DRUG	albendazole	albendazole (400 mg on dose)
DRUG	mebendazole	mebendazole (500 mg one dose)
DRUG	ivermectin	ivermectin (200 microgram/kg body weight)
DRUG	albendazole + ivermectin	albendazole (400 mg one dose) + ivermectin (200 mg microgram/kg body weight)
DRUG	mebendazole + ivermectin	mebendazole (500 mg one dose) + ivermectin (200 microgram/kg body weight)

Timeline

• Start date: 2007-10-01
• Primary completion: 2009-08-01
• Completion: 2009-08-01
• First posted: 2010-01-15
• Last updated: 2010-01-15

Locations

1 site across 1 country: Uganda