NCT01046968

Lepticore in Metabolic Syndrome and Weight Loss

The Use of LeptiCore® in Reducing Fat Gain and Managing Weight Loss in Patients With Metabolic Syndrome

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 92 (actual)
• Sponsor: University of Yaounde 1 · Academic / Other
• Sex: All
• Age: 19 Years – 52 Years
• Healthy volunteers: Accepted

Summary

Metabolic syndrome is directly related to obesity. This study investigated the use of a plant based formulation to improve on the condition of people with metabolic syndrome.

Detailed description

LeptiCore is a proprietary combination of various ingredients which have been shown to have properties which could be beneficial to weight loss in obese and overweight human subjects. This study evaluates the effect of Lepticore on bodyweight as well as parameters associated with obesity and metabolic syndrome. The study was an 8 week randomized, double-blind, placebo-controlled design involving 92 obese (mean BMI\>30kg/m2) participants (37 males; 55 females; ages 19-52; mean age = 30.7). The participants were randomly divided into three groups: placebo (n=30), LeptiCore formula A (low dose) (n=31) and LeptiCore formula B (high dose) (n=31). Capsules containing the placebo or active formulations were administered twice daily before meals with 300 ml of water. None of the participants followed any specific diet nor took any weight-reducing medications for the duration of the study. A total of 12 anthropomorphic and serological measurements were taken at the beginning of the study and after 2, 4, 6, and 8 weeks of treatment.

Conditions

• Obesity
• Hyperlipidemia
• Hyperglycemia

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Lepticore	300 mg twice daily

Timeline

• Start date: 2009-08-01
• Primary completion: 2009-11-01
• Completion: 2009-11-01
• First posted: 2010-01-12
• Last updated: 2010-01-12

Locations

1 site across 1 country: Cameroon