NCT01045824

Family-based Genetic Long-term Study of Brain Function in Schizophrenia

The Genetic Study of Longitudinal Brain Function Among Schizophrenic Patients With Family History

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 600 (estimated)
• Sponsor: Taichung Veterans General Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The goal of this research is to find out possible susceptible gene(s) in schizophrenic patients with family history and 5-year period functional changes of brain among the members of family, in order to further analysis factors and their interactions.

Detailed description

Schizophrenia is a serious mental disease, highly family inheritable inclination. By means of traditional psychiatry diagnosis, genetics and long term brain change researches will help to unveil the secret of schizophrenia and other factors. The advantage of comparative gene hybridization is that chromosome copy number alterations can be detected; this technique has been widely applied in many researches, such as cancer, mental retardation screening and autism. As we known, we are the first one use this technique in chromosome abnormality research for family history schizophrenic patient, this study also is the first one to track the relationship of long term brain function alteration and chromosome abnormality in Taiwan.

Conditions

• Schizophrenia
• Blooddraw
• MRI

Timeline

• Start date: 2008-01-01
• Primary completion: 2014-01-01
• Completion: 2014-01-01
• First posted: 2010-01-11
• Last updated: 2010-01-15

Locations

1 site across 1 country: Taiwan