NCT01042626

Oral Peptones Load in Normocalcemic and Hypercalcemic Primary Hyperparathyroidism and Healthy Subjects

Dissimilar PTH, Gastrin, and Ionized Calcium Response to Oral Peptones in Normocalcemic Primary Hyperparathyroidism, Hypercalcemic Primary Hyperparathyroidism and Healthy Subjects

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: University of Eastern Piedmont · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to assess if subjects with hyperparathyroidism with normal serum calcium levels have different responses in the calcium regulating hormonal handling compared to a) patients with primary hyperparathyroidism and high serum calcium levels; b) healthy subjects. The differences will be evaluated with oral peptones load and subsequent blood samples collected every 15 minutes for two hours. Ionized calcium, phosphate, gastrin and PTH levels will be evaluated.

Conditions

• Hyperparathyroidism
• Hypercalcemia

Interventions

Type	Name	Description
OTHER	Oral peptones load	Enrolled subjects will receive 10 g Liebig meat extract diluted in 250ml of 0.9% saline

Timeline

• Start date: 2004-07-01
• Primary completion: 2005-01-01
• Completion: 2005-01-01
• First posted: 2010-01-05
• Last updated: 2010-01-05

Locations

1 site across 1 country: Italy