NCT01042145

Community Care for Croup (RCT)

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 87 (actual)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: All
• Age: 1 Year – 8 Years
• Healthy volunteers: Not accepted

Summary

This randomized clinical trial was to compare the effectiveness of prednisone 2mg/kg/day for 3 days vs. dexamethasone 0.6mg/kg for 1 day for treatment of children with mild or moderate croup. It was conducted in a practice-based research network of community pediatricians in the St. Louis area. Outcomes included additional health care for croup, duration of symptoms, nights of disturbed sleep, parental stress, missed work days, and adverse events. Our hypothesis was that community-based treatment of children with mild or moderate croup with multiple doses of prednisone is superior to a single dose of dexamethasone.

Conditions

• Croup

Interventions

Type	Name	Description
DRUG	Prednisone	2 mgs/kg for 3 days
DRUG	Dexamethasone	0.6 mgs for one day, then placebo for 2 days

Timeline

• Start date: 2009-10-01
• Primary completion: 2011-06-01
• Completion: 2011-06-01
• First posted: 2010-01-05
• Last updated: 2014-09-15
• Results posted: 2014-09-15

Locations

1 site across 1 country: United States