NCT01037088

Effects of Vaporized Marijuana on Neuropathic Pain

CCRC: The Analgesic Effect of Vaporized Cannabis on Neuropathic Pain

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 44 (actual)
• Sponsor: University of California, Davis · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This study theorized that a low dose of vaporized cannabis could alleviate nerve injury pain.

Detailed description

We conducted a double-blind, placebo-controlled, crossover study evaluating the analgesic efficacy of vaporized cannabis in subjects, the majority of whom were experiencing neuropathic pain despite traditional treatment. Thirty-nine patients with central and peripheral neuropathic pain underwent a standardized procedure for inhaling medium-dose (3.53%), low-dose (1.29%), or placebo cannabis with the primary outcome being visual analog scale pain intensity. Psychoactive side effects and neuropsychological performance were also evaluated.

Conditions

• Neuropathic Pain
• Reflex Sympathetic Dystrophy
• Peripheral Neuropathy
• Post-herpetic Neuralgia
• Spinal Cord Injury
• Multiple Sclerosis

Interventions

Type	Name	Description
DRUG	Mild dose cannabis	3.53% THC by weight
DRUG	Low dose cannabis	1.29% THC by weight
DRUG	Cannabis	0.00% THC by weight

Timeline

• Start date: 2009-12-01
• Primary completion: 2012-11-01
• Completion: 2012-11-01
• First posted: 2009-12-21
• Last updated: 2018-01-31
• Results posted: 2013-04-09

Locations

1 site across 1 country: United States