Trials / Completed
CompletedNCT01032993
Clinical Trial of CoQ10 for Mild-to-Moderate Statin-Associated Muscle Symptoms
- Status
- Completed
- Phase
- Phase 2 / Phase 3
- Study type
- Interventional
- Enrollment
- 68 (actual)
- Sponsor
- Catherine Buettner · Academic / Other
- Sex
- All
- Age
- 21 Years
- Healthy volunteers
- Accepted
Summary
This study will evaluate whether a dietary supplement, coenzyme Q10 (CoQ10), will improve muscle symptoms, such as muscle aches, pains, cramps, and/or weakness, which are experienced by some individuals who use statin medications.
Detailed description
This study will recruit individuals who have had muscle symptoms while using a statin. During the first part of the study, volunteers will be given a statin medication to see if their muscle symptoms return. Those who experience muscle symptoms on this statin rechallenge will be invited to continue in the second part of the trial, in which participants will be randomly assigned to receive either CoQ10 or a placebo (sugar pill) to take with statin medication. We hypothesize that those who receive CoQ10 will experience an improvement in their muscle symptoms compared to those who receive placebo, and, secondarily, that those who receive CoQ10 will be more likely to continue taking the statin medication.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Coenzyme Q10 | 300 mg of CoQ10 (three 100 mg chewable tablets) 2 times daily for 4 weeks |
| OTHER | Placebo | Placebo (three chewable tablets) 2 times daily for 4 weeks |
Timeline
- Start date
- 2009-12-01
- Primary completion
- 2016-05-01
- Completion
- 2016-05-01
- First posted
- 2009-12-16
- Last updated
- 2017-01-23
- Results posted
- 2017-01-23
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01032993. Inclusion in this directory is not an endorsement.