Trials / Completed
CompletedNCT01032798
Local Anesthetics New Formulations: From Development to Clinical Tests
Efficacy and Pharmacokinetics of Liposomal Mepivacaine Formulations in Dentistry
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 30 (actual)
- Sponsor
- University of Campinas, Brazil · Academic / Other
- Sex
- All
- Age
- 20 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
This blinded cross-over study aim to evaluate the efficacy and the pharmacokinetics of a previously reported liposome-encapsulated mepivacaine formulations.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | mepivacaine | One intra-oral injection at four different sessions, of the following formulations: 2% mepivacaine with 1:100,000 epinephrine, 3% mepivacaine, 2% and 3% liposome-encapsulated mepivacaine. |
Timeline
- Start date
- 2007-05-01
- Completion
- 2008-05-01
- First posted
- 2009-12-16
- Last updated
- 2010-01-20
Locations
1 site across 1 country: Brazil
Source: ClinicalTrials.gov record NCT01032798. Inclusion in this directory is not an endorsement.