NCT01032213

Effect of Magnesium Sulphate on Coagulation

Effect of Magnesium Sulphate on Postoperative Coagulation as Measured by Thromboelastography

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Seoul National University Bundang Hospital · Academic / Other
• Sex: Female
• Age: 20 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Arterial and venous thrombotic events are the clinical manifestation of postoperative hypercoagulability. Altered serum magnesium may play a role in the balance of coagulation. In this study, the investigators investigated the effect of magnesium sulphate on the postoperative coagulation change in total intravenous anesthesia (TIVA).

Conditions

• Myoma

Interventions

Type	Name	Description
DRUG	Magnesium Sulfate	Group M received 50 mg/kg of magnesium sulphate on 100 ml of isotonic saline over 10 minutes during the anesthesia induction, followed by the 15 mg/kg/h by continuous infusion during the operation
DRUG	normal saline	Group S received the same volume of isotonic saline as same method.

Timeline

• Start date: 2010-01-01
• Primary completion: 2010-10-01
• Completion: 2010-10-01
• First posted: 2009-12-15
• Last updated: 2013-08-26

Locations

1 site across 1 country: South Korea