NCT01030757

Study of Stereotactic Body Radiation Therapy Using Tomotherapy for Metastatic Tumors to the Liver

Phase II Study of Stereotactic Body Radiation Therapy Using Tomotherapy for Metastatic Tumors to the Liver

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 2 (actual)
• Sponsor: New Mexico Cancer Research Alliance · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the response of liver tumors to radiation therapy using Tomotherapy.

Detailed description

The purpose of this study is to determine the response of liver tumors to radiation therapy. This study will be using a type of radiation therapy called tomotherapy. Tomotherapy is a relatively new kind of therapy which is able to focus a large amount of radiation to a small area with relatively less radiation to the surrounding non-cancerous part of the organ. This study is being done to find out if this technique is able to control the cancer better or not than the standard radiation and also to study its safety. The usual treatment for this type of disease for patients who are eligible is surgery to remove the tumors. For patients who aren't eligible for surgery or who chose not to have surgery, they are treated with low daily doses of radiation given over many weeks; however this type of treatment has not been very effective.

Conditions

• Liver Cancer

Interventions

Type	Name	Description
RADIATION	Tomotherapy treatment	* A total of 60 Gy using 12 Gy per fraction over 5 fractions to be given within 10 calendar days * Each fraction of 12 Gy will be divided into 2 fractions of 6 Gy given in one day within 6 hours * Dose will be prescribed to the isodose line which covers at least 90% of the PTV * Dose homogeneity +/- 5%

Timeline

• Start date: 2009-06-01
• Primary completion: 2013-05-01
• Completion: 2013-05-01
• First posted: 2009-12-11
• Last updated: 2015-07-07
• Results posted: 2015-07-07

Locations

1 site across 1 country: United States