NCT01028599

Effect of Physical Training on Oxygen Uptake and Endothelial Function in Heart Transplant Recipients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Rigshospitalet, Denmark · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate the effect of physical training on work capacity and vascular function after heart transplantation, cardiac transplant recipients are randomized to 8 weeks of intense physical training or control. Vascular function is measured non-invasively. Effect on the hormones and the immune system is evaluated using blood samples.

Detailed description

To investigate the effect of physical training on work capacity and vascular function after heart transplantation, cardiac transplant recipients are randomized to 8 weeks of intense physical training or control. Vascular function is measured non-invasively using forearm flow mediated dilatation. Effect on the blood natriuretic peptides and the inflammatory markers is evaluated using blood samples at baseline and after the training or control period.

Conditions

• Heart Transplantation
• Exercise Capacity
• Endothelial Function

Interventions

Type	Name	Description
OTHER	Intensive physical exercise	Intensive physical exercise 1 hour three times per week

Timeline

• Start date: 2009-09-01
• Primary completion: 2009-12-01
• Completion: 2010-01-01
• First posted: 2009-12-09
• Last updated: 2015-10-28