NCT01025518

DAHANCA 25A: Resistance Training and Dietary Supplements as Intervention for Regaining Muscle Mass Following Radiotherapy in Head and Neck Cancer Patients

A Randomized Trial Evaluating Resistance Training and Dietary Supplements as Intervention for Regaining Muscle Mass Following Radiotherapy in Head and Neck Cancer Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Danish Head and Neck Cancer Group · Network
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate whether resistance training in combination with dietary supplementation is tolerable among head and neck cancer patients and to evaluate the possible effect on muscle mass, strength and functional capacity.

Detailed description

Head and neck cancer patients experience a significant loss of muscle mass following radiotherapy treatment due to cachexia and dysphagia. This negatively affects muscle strength and functional capacity. Studies on healthy individuals and various groups of patients show that resistance training in combination with protein and creatine ingestion is an effective means of increasing muscle mass, strength and functional capacity. Thus the aim is to investigate the following: * is resistance training and dietary supplements tolerable among head and neck cancer patients * the effect of the intervention on muscle mass, strength and functional capacity

Conditions

• Head and Neck Neoplasms

Interventions

Type	Name	Description
OTHER	Resistance training	12 weeks of resistance training in combination with protein and creatine or placebo ingestion
DIETARY_SUPPLEMENT	Protein and creatine	30 g of protein with each training session, 5 g of creatine pr day
DIETARY_SUPPLEMENT	Placebo	Maltodextrine

Timeline

• Start date: 2009-09-01
• Primary completion: 2012-01-01
• Completion: 2012-01-01
• First posted: 2009-12-03
• Last updated: 2016-11-29

Locations

2 sites across 1 country: Denmark