NCT01023724

A Comparison of Post Phacoemulsification Aqueous Flare in Patients Using Ketorolac 0.45% 2 Times Daily (BID) and Bromfenac 0.09% 2 Times Daily (BID)

A Comparison of Post Phacoemulsification Aqueous Flare in Patients Using Ketorolac 0.45% BID and Bromfenac 0.09% BID

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Bucci Laser Vision Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Approximately 50 patients undergoing cataract surgery will be randomized in an even allocation (1:1) into two treatment groups, either ketorolac 0.45% BID or bromfenac 0.09% BID. Patients will be instructed to begin dosing study medication in the operative eye the day before surgery and continue dosing until day 14. KOWA flare measurements will be performed at postoperative day one and postoperative day 14. The amount of anterior chamber inflammation (flare) will be objectively measured.

Conditions

• Post Operative Anterior Chamber Inflammation (Flare)

Interventions

Type	Name	Description
DRUG	Ketorolac Tromethamine 0.45%	Acuvail to be given 1 drop BID for one day prior to surgery and then 1 drop BID post operatively for 14 days.
DRUG	Bromfenac 0.09%	Drug given one drop BID for one day pre operatively and then BID for 14 days post operatively

Timeline

• Start date: 2009-12-01
• Primary completion: 2010-01-01
• Completion: 2010-02-01
• First posted: 2009-12-02
• Last updated: 2011-08-26
• Results posted: 2011-08-26

Locations

1 site across 1 country: United States