NCT01022502

Comparison of Refined and Crude Indigo Naturalis Ointment in Treating Psoriasis

Efficacy and Safety Comparison Between Refined and Crude Indigo Naturalis Ointment in the Treatment of Psoriatic Vulgaris

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 38 (actual)
• Sponsor: Yin-ku Lin · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Accepted

Summary

To compare the efficacy and safety of refined indigo naturalis ointment with that of crude ointment in treating psoriasis.

Detailed description

Our previous studies have shown that topical application of indigo naturalis significantly improves psoriatic symptoms. However, patient compliance is hindered because the preparation is unsightly and stains clothing. To improve patient compliance, we have developed a refined formulation in which closer to natural skin tones and less prone to stain clothing. In this study, we evaluated the efficacy and safety of this refined form of oil extract ointment and compared the results with those of the original crude form of indigo naturalis ointment in treating psoriasis.

Conditions

• Psoriasis Vulgaris

Interventions

Type	Name	Description
DRUG	refined indigo naturalis ointment	The patients applied either refined oil extract or crude indigo naturalis ointmnet topically to each of two bilaterally symmetrical psoriatic plaque lesions for 8 weeks.
DRUG	crude indigo naturalis ointment	The patients applied either refined oil extract or crude indigo naturalis ointmnet topically to each of two bilaterally symmetrical psoriatic plaque lesions for 8 weeks.

Timeline

• Start date: 2009-11-01
• Primary completion: 2010-12-01
• Completion: 2010-12-01
• First posted: 2009-12-01
• Last updated: 2012-10-16
• Results posted: 2012-10-16

Locations

1 site across 1 country: Taiwan