Clinical Trials Directory

Trials / Completed

CompletedNCT01021358

A Study to Assess the Effect of Ketoconazole on the Metabolism of ABT-263 (Navitoclax).

A Phase 1 Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of ABT-263 (Navitoclax)

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
12 (estimated)
Sponsor
Abbott · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a single dose, open-label, single or multiple center study to determine the interaction of ketoconazole with ABT-263 in approximately 12 subjects with cancer.

Conditions

Interventions

TypeNameDescription
DRUGABT-263Subjects will be dosed with ABT-263, then dosed with ABT-263 in combination with Ketoconazole.
DRUGKetoconazoleSubjects will be dosed with ABT-263, then dosed with ABT-263 in combination with Ketoconazole.

Timeline

Start date
2010-01-01
Primary completion
2010-10-01
First posted
2009-11-30
Last updated
2010-12-20

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01021358. Inclusion in this directory is not an endorsement.