Clinical Trials Directory

Trials / Completed

CompletedNCT01019421

Lu AE58054 Added to Donepezil for the Treatment for Moderate Alzheimer's Disease

Randomised, Double-blind, Parallel-group, Placebo-controlled, Fixed-dose Study of Lu AE58054 in Patients With Moderate Alzheimer's Disease Treated With Donepezil

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
278 (actual)
Sponsor
H. Lundbeck A/S · Industry
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to accept or reject the hypothesis that Lu AE58054 improves cognition and functional outcomes in patients with moderate Alzheimer's Disease, already in treatment with donepezil.

Detailed description

Multi-centre, randomised, double-blind, parallel-group, placebo-controlled, fixed-dose study of Lu AE58054 as add-on to donepezil. The patient has probable Alzheimer's Disease consistent with the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) criteria.

Conditions

Interventions

TypeNameDescription
DRUGLu AE58054Add-on treatment to donepezil
DRUGPlaceboAdd-on treatment to donepezil

Timeline

Start date
2009-12-01
Primary completion
2011-12-01
First posted
2009-11-25
Last updated
2012-01-06

Locations

51 sites across 7 countries: Australia, Canada, Czechia, Germany, Italy, Poland, Spain

Source: ClinicalTrials.gov record NCT01019421. Inclusion in this directory is not an endorsement.