NCT01018134

Desoximetasone Spray 0.05%, 0.25%; Dose Ranging Study

A Double-Blind, Vehicle-Controlled, Randomized, Dose Ranging, Multiple-Site Clinical Study to Evaluate the Efficacy and Safety of Desoximetasone Topical Sprays (0.05%, 0.25%) in Patients With Moderate to Severe Plaque Psoriasis

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 151 (actual)
• Sponsor: Sun Pharmaceutical Industries, Inc. · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The objectives of this study are to evaluate the efficacy and safety of two dosing regimens of desoximetasone 0.05% and 0.25% topical sprays as compared to a vehicle spray in patients with moderate to severe plaque psoriasis.

Conditions

• Psoriasis

Interventions

Type	Name	Description
DRUG	Desoximetasone 0.05% once daily	Desoximetasone topical spray 0.05% administered to affected area once daily for 28 days
DRUG	Desoximetasone 0.05% twice daily	Desoximetasone topical spray 0.05% administered to affected area twice daily for 28 days
DRUG	Desoximetasone 0.25% once daily	Desoximetasone topical spray 0.25% administered to affected area once daily for 28 days
DRUG	Desoximetasone 0.25% once daily	Desoximetasone topical spray 0.25% administered to affected areas twice daily for 28 days
DRUG	Vehicle once daily	Vehicle topical spray administered to affected areas once daily for 28 days
DRUG	Vehicle twice daily	Vehicle topical spray administered to affected areas twice daily for 28 days

Timeline

• Start date: 2009-11-01
• Primary completion: 2010-05-01
• Completion: 2010-05-01
• First posted: 2009-11-23
• Last updated: 2014-08-05
• Results posted: 2014-08-05

Locations

7 sites across 1 country: United States