NCT01015183

Prevention Chemotherapy Induced Mucositis by Zinc Sulfate

Prevention High Dose Chemotherapy Induced Mucositis by Using Zinc Sulfate

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Tehran University of Medical Sciences · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

In this double blinded randomized study we evaluate effect of Zinc sulfate for prevention mucositis due to high dose chemotherapy in the patients undergoing bone marrow transplantation whose received Busulfan and/or Cyclophosphamide. Patients randomized in two groups: intervention and control with balanced block randomization method. Intervention group received Zinc sulfate immediately after start conditioning regimen and continued for two weeks. Control group received placebo at the same manner. Prevalence and severity of mucositis will be compared in two groups.

Conditions

• Mucositis
• Bone Marrow Transplantation

Interventions

Type	Name	Description
DRUG	Zinc Sulfate	Zinc Sulfate: 100 mg of zinc element, per day, bid for two weeks start with chemotherapy
DRUG	Placebo	Placebo: as the same of intervention group

Timeline

• Start date: 2009-11-01
• Primary completion: 2010-11-01
• Completion: 2011-06-01
• First posted: 2009-11-18
• Last updated: 2011-07-26

Locations

1 site across 1 country: Iran