NCT01012414

Effect of Vitamin D Supplement on Inflammation Markers in High-Risk Cardiovascular Patients With Chronic Kidney Disease

The Effect of Vitamin D Supplementation on Markers of Inflammation in High-Risk Cardiovascular Patients With Low Levels of Serum 25-Hydroxyvitamin D

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Thomas Jefferson University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine if vitamin D supplementation changes the results of certain tests associated with inflammation in the body using an oral, synthetic form of vitamin D called paricalcitol.

Detailed description

Vitamin D deficiency is common and has been associated with an increased risk of heart disease. In patients with the combination of kidney disease and heart disease, inflammation is thought to contribute to a high rate of cardiac events. Less is known about the effects of vitamin D supplementation on certain tests associated with inflammation in the body.

Conditions

• Coronary Artery Disease
• Chronic Kidney Disease
• Hypovitaminosis D
• Secondary Hyperparathyroidism

Interventions

Type	Name	Description
DRUG	paricalcitol	2 mcg oral paricalcitol daily
DRUG	placebo	placebo

Timeline

• Start date: 2010-01-01
• Primary completion: 2011-05-01
• Completion: 2011-05-01
• First posted: 2009-11-13
• Last updated: 2014-05-20
• Results posted: 2013-11-11

Locations

1 site across 1 country: United States