Clinical Trials Directory

Trials / Terminated

TerminatedNCT01009957

Everolimus on CKD Progression in ADPKD Patients

Everolimus on CKD (Chronic Kidney Disease) Progression in ADPKD Patients

Status
Terminated
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
71 (actual)
Sponsor
A. Manzoni Hospital · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The study will evaluate whether the administration of everolimus (1.5 mg/day) can slow down the progression of CKD in ADPKD patients.

Detailed description

Considering the inhibitor activity of Everolimus on mTOR, our hypothesis is to evaluate its possible utility on the progression of CKD in ADPKD patients by reducing the rate of increase of renal cysts.

Conditions

Interventions

TypeNameDescription
DRUGEverolimus0.75 mg x 2 / day

Timeline

Start date
2008-06-01
Primary completion
2014-01-01
Completion
2015-06-01
First posted
2009-11-09
Last updated
2015-06-23

Locations

7 sites across 1 country: Italy

Source: ClinicalTrials.gov record NCT01009957. Inclusion in this directory is not an endorsement.