NCT01008826

Cross-Over Broccoli Sprouts Trial

Cross-Over Broccoli Sprouts Trial - Qidong

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Johns Hopkins Bloomberg School of Public Health · Academic / Other
• Sex: All
• Age: 25 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The study hypothesis tested is that broccoli sprouts are effective at altering the urinary levels of metabolites of the hepatocarcinogen aflatoxin B1 and of the air-borne pollutant phenanthrene in residents of Qidong, PRC, where exposures are unavoidable and high. The study will evaluate which of two formulations of broccoli sprouts beverage, glucoraphanin-rich or sulforaphane-rich, exhibits the best bioavailability and is most effective at modulating the biomarkers.

Conditions

• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	broccoli sprouts extract	Glucoraphanin-rich broccoli sprouts extract: 800 micromoles daily for 7 days dissolved in 100 mL of dilute mango juice Sulforaphane-rich broccoli sprouts extract: 150 micromoles daily for 7 days dissolved in 100 mL of dilute mango juice

Timeline

• Start date: 2009-10-01
• Primary completion: 2009-11-01
• Completion: 2009-12-01
• First posted: 2009-11-06
• Last updated: 2011-09-16

Locations

1 site across 1 country: China