Clinical Trials Directory

Trials / Completed

CompletedNCT01007539

Efficacy and Safety of CDP-choline in Patients With Methamphetamine Dependence

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
31 (actual)
Sponsor
Seoul National University Hospital · Academic / Other
Sex
All
Age
19 Years – 60 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to determine if cytidine 5'diphosphocholine (CDP-choline, a naturally occurring chemical in your body) has efficacy in reducing the methamphetamine craving of the subjects with methamphetamine dependence craving and helping them maintain the abstinence. In addition, investigators will measure the brain N-acetyl aspartate (a biologic marker for neuronal viability) level of participants to determine if brain deficits induced by methamphetamine may recover by taking CDP-choline.

Conditions

Interventions

TypeNameDescription
DIETARY_SUPPLEMENTCDP-cholineThe subjects will be given 1g citicoline twice daily for a total of 8 weeks.
DIETARY_SUPPLEMENTPlacebo (fructose)The Subjects will be given 2 tablets of placebo twice daily for 8 weeks. They will be taking the same quantity as the CDP-choline group.

Timeline

Start date
2009-11-01
Primary completion
2012-01-01
Completion
2012-01-01
First posted
2009-11-04
Last updated
2012-08-31

Locations

2 sites across 1 country: South Korea

Source: ClinicalTrials.gov record NCT01007539. Inclusion in this directory is not an endorsement.