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UnknownNCT01007240

Antibacterial Properties of Silicon Incorporated With Quaternary Ammonium Polyethylenimine Nanoparticles

Clinical Study of the Antibacterial Properties of the Nano Particles Which Incorporated With the Soft Liner Silicone - in Obturators

Status
Unknown
Phase
Phase 1
Study type
Interventional
Enrollment
10 (estimated)
Sponsor
Hadassah Medical Organization · Academic / Other
Sex
All
Age
18 Years – 90 Years
Healthy volunteers
Not accepted

Summary

The aim of this study is to evaluate the antibacterial activity of crosslinked quaternary ammonium polyethylenimine (PEI) nanoparticles incorporated at 1-2% w/w in a commercial soft liner material when compared to the commercial soft liner material. The investigators' results in vitro showed a significant delay in bacterial growth. Therefore, the investigators assume to have the same delay in vivo- on patients.

Conditions

Interventions

TypeNameDescription
DEVICEpolyethylenimine (PEI) nanoparticles.

Timeline

Start date
2010-01-01
Primary completion
2010-05-01
Completion
2010-12-01
First posted
2009-11-04
Last updated
2009-11-04

Source: ClinicalTrials.gov record NCT01007240. Inclusion in this directory is not an endorsement.

Antibacterial Properties of Silicon Incorporated With Quaternary Ammonium Polyethylenimine Nanoparticles (NCT01007240) · Clinical Trials Directory