Clinical Trials Directory

Trials / Completed

CompletedNCT01005277

Study of Biomarkers in DNA Samples From Patients With Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia

Genetic Polymorphisms in ALL Samples Submitted to Gene Array Analysis

Status
Completed
Phase
—
Study type
Observational
Enrollment
2,000 (estimated)
Sponsor
Children's Oncology Group · Network
Sex
All
Age
—
Healthy volunteers
Not accepted

Summary

This research study is looking at biomarkers in DNA samples from patients with acute lymphoblastic leukemia or acute myeloid leukemia. Studying samples of DNA from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.

Detailed description

PRIMARY OBJECTIVES: I. Collect DNA samples from patients with cytogenetically, well characterized, and uniformly treated acute lymphoblastic leukemia or acute myeloid leukemia for use in analysis of a wide range of host factors influencing etiology and outcome of the disease. II. Identify host factors that can be determined at onset of treatment to predict outcome of chemotherapy, and thus modify the therapy administered. OUTLINE: Previously collected DNA samples are analyzed for polymorphisms at a variety of loci. Gene expression and expression profiles are correlated with genotype and therapy outcomes.

Conditions

Interventions

TypeNameDescription
OTHERLaboratory Biomarker AnalysisCorrelative studies

Timeline

Start date
2002-04-17
Primary completion
2016-05-05
First posted
2009-10-30
Last updated
2022-07-14

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01005277. Inclusion in this directory is not an endorsement.

Study of Biomarkers in DNA Samples From Patients With Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia (NCT01005277) · Clinical Trials Directory