Trials / Unknown
UnknownNCT01005173
Acetaminophen Biomarkers
Identification of New Mechanistic Biomarkers of Adverse Response to Acetaminophen
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 253 (estimated)
- Sponsor
- Arkansas Children's Hospital Research Institute · Academic / Other
- Sex
- All
- Age
- 1 Year – 18 Years
- Healthy volunteers
- Accepted
Summary
This study is a non-intervention, multicenter study to address biomarkers of acetaminophen toxicity in children. Specifically, the study will examine acetaminophen (APAP) protein adducts and markers of liver injury in the blood samples of hospitalized children and adolescents who are receiving standard doses of acetaminophen, and children and adolescents who are status post acetaminophen overdose. Ultimately, the data generated from this study will be used to establish second generation biomarkers of acetaminophen toxicity, based on specific adduct proteins, which can be used in future risk assessment studies of children receiving acetaminophen.
Conditions
Timeline
- Start date
- 2009-08-01
- Primary completion
- 2018-06-01
- First posted
- 2009-10-30
- Last updated
- 2017-11-24
Locations
8 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT01005173. Inclusion in this directory is not an endorsement.