NCT01005082

Low Salt Diet in Idiopathic Hypercalciuria

Calcium Nephrolithiasis: Clinical Characteristics and Nutritional Determinants

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 210 (actual)
• Sponsor: University of Parma · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: —

Summary

Randomized clinical trial comparing water therapy plus low-salt diet to water therapy alone in patients affected by idiopathic calcium nephrolithiasis. Treatment duration: three months Primary end-point: correction of hypercalciuria Main inclusion criteria: calcium stone formers with idiopathic hypercalciuria, with at least one stone expelled and analyzed by infrared spectrophotometry; presence of hypercalciuria (\>300 mg/day in males and \>200 mg/day in females); 18-65 years. Main exclusion criteria: primary hyperparathyroidism, primary hyperoxaluria, enteric hyperoxaluria, bowel resection, inflammatory bowel disease, renal tubular acidosis, sarcoidosis, sponge kidney, hyperthyroidism, use of hypercalciuric drugs such as Vitamin D, acetazolamide, anti-epileptic drugs

Conditions

• Hypercalciuria

Interventions

Type	Name	Description
BEHAVIORAL	Low salt diet
BEHAVIORAL	Water therapy alone

Timeline

• Start date: 2005-01-01
• Primary completion: 2008-09-01
• Completion: 2008-12-01
• First posted: 2009-10-30
• Last updated: 2009-10-30

Locations

1 site across 1 country: Italy