NCT01003548

Embryo Development in Microfluidics System of Culture

Comparison of the in Vitro Development of Human Embryos in Static and and Microfluidics Systems of Culture

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 400 (estimated)
• Sponsor: Federal University of São Paulo · Academic / Other
• Sex: Female
• Age: 21 Years – 35 Years
• Healthy volunteers: Accepted

Summary

Embryo culture is a cornerstone of in vitro fertilization treatments. Usually, embryos are cultured in microdrops of culture media in incubators with controlled temperature, humidity and atmosphere. However, these culture systems are static, while in vivo the initial growth of the embryo takes place in the uterine tube and they are submitted to a dynamic environment. The aim of this study is to compare the embryo development on days 2 and 3 of culture morphological features of embryos under static and dynamic(microfluidics) systems of culture.

Detailed description

Embryo culture is a cornerstone of in vitro fertilization treatments. Usually, embryos are cultured in microdrops of culture media in incubators with controlled temperature, humidity and atmosphere. However, these culture systems are static, while in vivo the initial growth of the embryo takes place in the uterine tube and they are submitted to a dynamic environment. The aim of this study is to compare the embryo development on days 2 and 3 of culture morphological features of embryos under static and dynamic(microfluidics) systems of culture.

Conditions

• Infertility

Interventions

Type	Name	Description
DEVICE	SMART dynamic system of embryo culture	Embryos will be cultured in a dynamic system of microfluidics.
DEVICE	Static culture	Embryos cultured in 40 microliters microdrops of G-IVF plus series V

Timeline

• Start date: 2009-10-01
• Primary completion: 2010-10-01
• Completion: 2011-10-01
• First posted: 2009-10-28
• Last updated: 2009-10-28

Locations

1 site across 1 country: Brazil