NCT01000181

Imaging 61CuATSM Uptake in Atherosclerotic Plaque Using PET-CT

A Mechanistic, Non-randomised Study to Examine the Uptake of a Specific Radionuclide (61CuATSM) in Carotid Artery Plaque

• Status: Suspended
• Phase: —
• Study type: Observational
• Enrollment: 10 (estimated)
• Sponsor: King's College London · Academic / Other
• Sex: All
• Age: 55 Years
• Healthy volunteers: Not accepted

Summary

The build up of plaque in the wall of the artery supplying blood to the brain poses a risk of stroke when the plaques become unstable and fragile. It is important to determine which patients are most at risk so that surgery can be performed. There is evidence that the risk is greatest when these plaques become oxygen deficient (hypoxic). The investigators wish to use PET imaging to identify hypoxic plaque, to help decide whether and when to perform surgery. The investigators have developed radiotracers (imaging agents) for this purpose, and this study is to determine whether they will work in patients.

Conditions

• Carotid Atherosclerosis

Interventions

Type	Name	Description
OTHER	PET-CT with CuATSM	PET-CT with CuATSM

Timeline

• Start date: 2012-10-01
• First posted: 2009-10-22
• Last updated: 2012-04-06

Locations

1 site across 1 country: United Kingdom