NCT00999687

Evaluation of the Efficacy and Safety of Indigo Naturalis Oil Extract on Psoriatic Nails

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 31 (actual)
• Sponsor: Chang Gung Memorial Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate efficacy and safety of indigo naturalis oil extract in treating nail psoriasis.

Detailed description

Nail psoriasis treatment is notoriously difficult. While indigo naturalis has been demonstrated safe and effective in treating skin psoriasis, its effect on nail psoriasis remains unverified.

Conditions

• Nail Psoriasis

Interventions

Type	Name	Description
DRUG	Indigo Naturalis Extract in Oil	Indigo naturalis extract in oil (INEO) was applied to the fingernails of one bilateral hand (experimental group) twice daily for the first 12 weeks. INEO was applied to all affected nails on both hands twice daily for another 12 weeks
OTHER	Olive Oil	Olive oil was applied to the fingernails of the contra-lateral hand (control group) twice daily for the first 12 weeks. INEO was applied to all affected nails on both hands twice daily for another 12 weeks.

Timeline

• Start date: 2009-09-01
• Primary completion: 2010-09-01
• Completion: 2010-09-01
• First posted: 2009-10-22
• Last updated: 2019-08-07
• Results posted: 2012-09-12