NCT00998361

Hematopoietic Stem Cell Transplantation From Human Leukocyte Antigen (HLA) Compatible Donor in Ewing Sarcomas and Soft Tissues Sarcomas

Hematopoietic Stem Cell Transplantation From HLA Compatible Donor in Ewing Sarcomas and Soft Tissues Sarcomas

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 140 (actual)
• Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna · Academic / Other
• Sex: All
• Age: 1 Month – 60 Years
• Healthy volunteers: Not accepted

Summary

This is a perspective multicentric study for the treatment of patients aged equal or less than 60 years and submitted to an allogeneic hematopoietic stem cell transplantation from an HLA compatible related or unrelated donor because affected by resistent or refractory or relapsed after autologous stem cell transplantation Ewing Sarcoma or Soft tissues sarcoma who did not benefit from conventional therapy.

Conditions

• Ewing
• Soft Tissue Sarcoma

Interventions

Type	Name	Description
PROCEDURE	Allogeneic hemopoietic stem cell transplant	administration of 15 mg/kg of thiotepa + 140 mg/sqm of melphalan followed by infusion of allogeneic hemopoietic stem cell

Timeline

• Start date: 2009-06-01
• Primary completion: 2010-06-01
• Completion: 2011-06-01
• First posted: 2009-10-20
• Last updated: 2009-10-20

Locations

1 site across 1 country: Italy