NCT00997269

Benefit of CoQ-10 in Patients on Statins

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 37 (actual)
• Sponsor: Stony Brook University · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

This study will investigate whether a supplement called co-enzyme Q10 can help ease or eliminate some of the side effects that result from taking statin medications. These side effects include muscle pain, fatigue or muscle cramping.

Detailed description

Specific Aim 1: to demonstrate that supplementation with coQ10 in patients treated with statins ameliorates symptoms of muscle pain and fatigue and improves energy metabolism and muscle function. This objective will be achieved in a randomized, placebo-controlled double blind trial by assessing the degree of muscle symptoms and interference of pain with daily activities, aerobic capacity, and muscle function before and after supplementation with either coQ10 or placebo in groups of statin-treated subjects. Specific Aim 2: to examine changes at a molecular/cellular level that are associated with improved pain and muscle function in statin-treated subjects supplemented with coQ10. This aim will be addressed by analyzing muscle biopsies taken from statin-treated patients before and after supplementation with coQ10 or placebo.

Conditions

• Pain
• Soreness
• Weakness
• Fatigue

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Co-enzyme Q-10	Patients will be supplemented with 300 mg of CoQ-10 1 time daily for one month
DIETARY_SUPPLEMENT	Placebo	Patients will be supplemented with CoQ-10 placebo 1 time daily for one month

Timeline

• Start date: 2009-09-01
• Primary completion: 2014-07-01
• Completion: 2014-07-01
• First posted: 2009-10-19
• Last updated: 2016-05-02

Locations

1 site across 1 country: United States