Clinical Trials Directory

Trials / Terminated

TerminatedNCT00996255

Dose-Escalation Study of PHA-793887 in Patients With Advanced/Metastatic Solid Tumors

A Phase I Dose-Escalation Study of PHA-793887 Administered as a 1-hour IV Infusion on Days 1, 8 and 15 in a 4-Week Cycle in Patients With Advanced/Metastatic Solid Tumors

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
19 (actual)
Sponsor
Nerviano Medical Sciences · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this open-label, multi center, phase I study, was to determine the safety profile of PHA-793887 administered by intravenous infusion to patients with advanced/metastatic solid tumors. This was a dose-finding study to determine the maximum tolerated dose and the dose of PHA-793887 that can be safely used in phase II investigations.

Conditions

Interventions

TypeNameDescription
DRUGPHA-793887Escalating doses of PHA-793887 administered weekly by IV infusion for 3 consecutive weeks in 4-week cycles.

Timeline

Start date
2006-11-01
Primary completion
2008-02-01
Completion
2008-02-01
First posted
2009-10-16
Last updated
2009-10-16

Locations

2 sites across 2 countries: France, United Kingdom

Source: ClinicalTrials.gov record NCT00996255. Inclusion in this directory is not an endorsement.