Clinical Trials Directory

Trials / Completed

CompletedNCT00995787

Safety and Tolerability of AZD1656 in Type 2 Diabetes Mellitus (T2DM) Patients Treated With Metformin and Sulfonylurea

A Randomized, Single-blind, Placebo-controlled, Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1656 Compared to Placebo in T2DM Patients Treated With Metformin and Sulfonylurea

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
75 (actual)
Sponsor
AstraZeneca · Industry
Sex
All
Age
30 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The primary aim of this study is to evaluate the safety and tolerability of AZD1656 in T2DM patients treated with metformin and sulfonylurea.

Conditions

Interventions

TypeNameDescription
DRUGAZD1656Dose titration of oral suspension of AZD165 during 3 days to a tolerable dose given twice daily. Subjects will thereafter be treated with this dose twice daily for another 6 days
DRUGPlaceboDose titration of oral suspension of placebo during 3 days given twice daily. Subjects will thereafter be for another 6 days

Timeline

Start date
2009-10-01
Primary completion
2010-02-01
Completion
2010-02-01
First posted
2009-10-15
Last updated
2010-02-26

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00995787. Inclusion in this directory is not an endorsement.