NCT00994942

Bioequivalency Study of Morphine Sulfate Injection, Solution and Tablet Under Fasted Conditions

A Single Dose, Three-Period, Three-Treatment, Six-Sequence, Three-Way Crossover Pharmacokinetic and Comparative Bioavailability Study of Morphine Sulfate Injection, Solution, and Tablet Formulations Under Fasting Conditions.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: Roxane Laboratories · Industry
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

Determine the pharmacokinetics and optimize study design for subsequent studies with morphine sulfate tablets and solution.

Conditions

• Pain

Interventions

Type	Name	Description
DRUG	morphine sulfate	morphine sulfate 30 mg tablet, morphine sulfate 30 mg (10 mg / 5 mL) oral solution, morphine sulfate injection 10 mg (1 mg / mL)

Timeline

• Start date: 2006-04-01
• Primary completion: 2006-04-01
• Completion: 2006-04-01
• First posted: 2009-10-14
• Last updated: 2018-01-23

Locations

1 site across 1 country: United States