Trials / Completed
CompletedNCT00994708
The Effect of Esomeprazole and Fundoplication on Airways
The Effect of Esomeprazole and Nissen Fundoplication on Bronchial Responsiveness, Quality of Life, Exhaled Nitric Oxide and Pulmonary Function in Patients With Gastroesophageal Reflux Disease
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- Tampere University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Evaluate the prevalence of bronchial responsiveness (BHR) among patients with gastroesophageal reflux disease (GERD). Investigate correlation between bronchial reactivity and the severity of GERD, and similarly investigate the correlation between exhaled nitric oxide (NO) and the severity of GERD. Compare the effects of esomeprazole 40 mg twice daily and Nissen fundoplication on bronchial reactivity, exhaled NO, pulmonary function and quality of life.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | esomeprazole |
Timeline
- Start date
- 2004-12-01
- First posted
- 2009-10-14
- Last updated
- 2009-10-14
Locations
1 site across 1 country: Finland
Source: ClinicalTrials.gov record NCT00994708. Inclusion in this directory is not an endorsement.