NCT00994383

Comparative Bioavailability Study of Morphine Sulfate Immediate Release and Controlled Release

A Single Dose, Three-Period, Three-Treatment, Six-Sequence, Three-Way Crossover Comparative Bioavailability Study of Morphine Sulfate Immediate Release Tablets and Solution and Controlled Release Capsules Under Steady-State Conditions.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Roxane Laboratories · Industry
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

Characterize the steady-state pharmacokinetics of morphine after oral administration of Roxane Laboratories' morphine sulfate immediate release tablets and oral solution and to compare their pharmacokinetics to that of AVINZA.

Conditions

• Pain

Interventions

Type	Name	Description
DRUG	morphine sulfate	morphine sulfate 30 mg tablet, morphine sulfate 15 mg tablet, morphine sulfate controlled release 120 mg

Timeline

• Start date: 2007-01-01
• Primary completion: 2007-01-01
• Completion: 2007-01-01
• First posted: 2009-10-14
• Last updated: 2018-01-23

Locations

1 site across 1 country: United States