NCT00991042

Study of Cytokines Serum Levels in Chronic Low Back Pain

Analytical Transversal Study of Cytokines Serum Levels in Chronic Low Back Pain Due to Herniated Disk

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: Federal University of São Paulo · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to: * evaluate if there is an association between elevated levels of cytokines and chronic pain due to herniated disk disease * measured cytokines levels in chronic low back pain and in healthy subjects.

Detailed description

23 patients with at least three months of back pain due to herniated disk disease were selected Diagnosis was confirmed by magnetic resonance imaging (MRI) or computerized tomography (CT) imaging of the spine for all patients. In addition, pain severity had to be ³ 5 points on the Numerical Rating Scale (NRS) ranging from zero (no pain) to 10 (worst imaginable pain). The exclusion criteria were defined as one or more of the following: psychiatric disorders, systemic or inflammatory disease, history of allergy, presence of motor deficits, history of blood dyscrasia, pregnancy, active infection, tumor, use of analgesic drugs in the week before or inability to come to the hospital for evaluation.

Conditions

• Interleukines

Interventions

Type	Name	Description
OTHER	blood collect	Five milliliters of venous blood was drawn in the morning from subjects and immediately centrifuged.

Timeline

• Start date: 2003-08-01
• Primary completion: 2004-09-01
• Completion: 2005-03-01
• First posted: 2009-10-07
• Last updated: 2009-10-07

Locations

1 site across 1 country: Brazil