Clinical Trials Directory

Trials / Completed

CompletedNCT00990223

Effects Of Eplerenone On Serum Aldesterone And Plasma Renin Activity

A Phase 1, Double-Blind (Sponsor Open), Randomized, Placebo-Controlled Trial To Evaluate The Effects Of 100 MG Once Daily Of Eplerenone On Serum Aldesterone And Plasma Renin Activity During 10 Days Of Dosing In Healthy Volunteers

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
20 (actual)
Sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · Industry
Sex
Male
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

To evaluate the changes in serum aldosterone and plasma renin activity on Day 0 and on Days 1 and 10 after administration of 100 mg of eplerenone daily for 10 days.

Conditions

Interventions

TypeNameDescription
DRUGEplerenone or PlaceboEplerenone 100 mg or Placebo, daily for 10 days.

Timeline

Start date
2009-10-01
Primary completion
2009-11-01
Completion
2009-11-01
First posted
2009-10-06
Last updated
2020-12-22

Locations

2 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00990223. Inclusion in this directory is not an endorsement.