NCT00989014

Dose-Finding Study of CD07805/47 Topical Gel in Subjects With Erythematotelangiectatic Rosacea

Randomized, Double-Blind, Parallel-Group, Vehicle-Controlled, Dose-Finding Study Investigating the Pharmacodynamics and Safety of Three Concentrations of CD07805/47 Topical Gel (0.07%, 0.18%, and 0.50%), Applied in Subjects With Moderate to Severe Erythematotelangiectatic Rosacea

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 122 (actual)
• Sponsor: Galderma R&D · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a randomized, double-blind, parallel-group, vehicle-controlled, dose-finding study to investigate the pharmacodynamics and the safety of three dosages of CD07805/47 topical gel (0.07%, 0.18%, and 0.50%), after a single application in subjects with a clinical diagnosis of stable moderate to severe erythematotelangiectatic rosacea. Subjects will be randomized in a 1:1:1:1 ratio to receive either one of three CD07805/47 topical gel concentrations (0.07%, 0.18%, or 0.50%) or Vehicle Gel. All subjects will be treated with a single application (once daily dosing for one day) of study medication.

Conditions

• Erythematotelangiectatic Rosacea

Interventions

Type	Name	Description
DRUG	CD07805/47	0.5% Topical Gel
DRUG	CD07805/47	0.18% Topical Gel
DRUG	CD07805/47	0.07% Topical Gel
DRUG	CD07805/47 placebo	Vehicle Topical Gel

Timeline

• Start date: 2009-09-01
• Primary completion: 2009-11-01
• Completion: 2009-12-01
• First posted: 2009-10-02
• Last updated: 2021-02-18
• Results posted: 2013-11-21

Locations

5 sites across 1 country: United States