NCT00988468

Manual Therapy Versus Exercise on Knee Osteoarthritis

Effects of Manual Therapy Versus Therapeutic Exercise on Knee Osteoarthritis: A Randomized Control Trial

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 1 (actual)
• Sponsor: Texas Tech University Health Sciences Center · Academic / Other
• Sex: All
• Age: 18 Years – 89 Years
• Healthy volunteers: Accepted

Summary

Earlier research has shown that exercising while receiving manual therapy improves function and reduces pain in people with knee osteoarthritis. However, very little is known about the mechanisms by which manual therapy and exercise reduce pain and improve function. This study will ask subjects with knee osteoarthritis to receive one of the following interventions: (1) no treatment, (2) exercise only, or (3) manual therapy only. Measures will be taken of the patient's knee range of motion, knee swelling and pain before and after receiving the intervention. These measures will be analyzed to determine what effect exercise and manual therapy applied to the knee have on improving knee range of motion and reducing knee pain and swelling. Swelling will be measured using an ultrasound device which is used to take pictures inside the knee. This type of ultrasound measurement is painless and harmless.

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
PROCEDURE	Manual Therapy	Grade 1 and 2 oscillatory manual mobilization of the tibiofemoral joint at various ranges of motion.
BEHAVIORAL	Therapeutic Exercise	Subjects will perform 5 minutes of lower extremity cycle ergometer with minimal resistance followed by 10 minutes of resistance exercise to the quadriceps at 3 tibiofemoral positions (0 degrees, 30 degrees and 60 degrees of knee flexion).
BEHAVIORAL	Video Observation	Subjects will watch a 15 minute video on a health topic unrelated to knee osteoarthritis.

Timeline

• Start date: 2009-10-01
• Primary completion: 2010-05-01
• Completion: 2010-08-01
• First posted: 2009-10-02
• Last updated: 2010-11-16

Locations

1 site across 1 country: United States