NCT00987402

Study of the Efficacy of Plain Soap and Water Versus Alcohol-based Rubs for Surgical Hand Preparation

Surgical Site Infections: a Cluster-randomized, Cross-over Study of the Efficacy of Plain Soap and Water Versus Alcohol-based Rubs for Surgical Hand Preparation

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 3,317 (actual)
• Sponsor: University Hospital, Geneva · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Surgical site infections (SSI) constitute a significant health-economic and clinical challenge. The investigators conducted a cluster-randomized, cross-over study to compare the efficacy of plain soap and water (PSW), used ubiquitously across sub-Saharan Africa for surgical hand preparation, to alcohol-based hand rub (ABHR), with SSI rates as the main outcome measure. A total of 3317 patients undergoing clean and clean-contaminated surgery were included in the study and followed up for 30 days.

Conditions

• Postoperative Wound Infection

Interventions

Type	Name	Description
OTHER	Plain soap and water (PSW)	Presence or absence of infection
OTHER	Alcohol-based hand rub (ABHR)	Presence or absence of infection

Timeline

• Start date: 2007-01-01
• Primary completion: 2007-11-01
• Completion: 2007-11-01
• First posted: 2009-10-01
• Last updated: 2012-08-21
• Results posted: 2012-08-21

Locations

1 site across 1 country: Kenya