Trials / Completed
CompletedNCT00985699
S8516-S8736-S9125-S9240 Research Study of Genes in Tissue Samples From Patients With B-cell Non-Hodgkin Lymphoma
Pharmacogenomics of Oxidative Stress-Related Genes in Lymphoma
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 337 (actual)
- Sponsor
- SWOG Cancer Research Network · Network
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study is looking at genes in tissue samples from patients with B-cell non-Hodgkin lymphoma.
Detailed description
OBJECTIVES: * To determine if toxicity following treatment for lymphoma varies according to genetic polymorphisms in oxidative stress-related genes (i.e., SOD2, CAT, GPX1, GSTM1, and GSTP1). * To assess whether these genetic polymorphisms are associated with progression-free survival and/or overall survival in these patients treated for lymphoma. OUTLINE: Previously collected samples are used for biomarker analysis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | polymorphism analysis | |
| OTHER | laboratory biomarker analysis | |
| OTHER | pharmacogenomic studies |
Timeline
- Start date
- 2009-04-01
- Primary completion
- 2014-06-01
- Completion
- 2014-06-01
- First posted
- 2009-09-28
- Last updated
- 2014-07-24
Source: ClinicalTrials.gov record NCT00985699. Inclusion in this directory is not an endorsement.