NCT00978692

Toric Orthokeratology - Slowing Eye Elongation

Toric Orthokeratology for Slowing Eye Elongation in Astigmatic Children

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: The Hong Kong Polytechnic University · Academic / Other
• Sex: All
• Age: 6 Years – 12 Years
• Healthy volunteers: Accepted

Summary

The aims of this study are to investigate the effects of ortho-k for astigmatic and myopic reduction and myopic control in children, and the long term effects on corneal curvatures and biomechanics.

Detailed description

Ortho-k has been shown to be effective in correcting low myopia but relatively ineffective for astigmatism, using spherical reverse geometry lens designs. Toric ortho-k lenses have been introduced in recent years but the efficacy for astigmatic reduction and for myopic control in children have not been confirmed. The mechanism of myopic reduction in ortho-k cannot be fully explained by changes to the anterior corneal curvatures. It is therefore possible that other corneal parameters such as posterior corneal curvature and corneal biomechanics may contribute to the mechanism. The current study aims at investigating the efficacy of toric ortho-k lenses for correcting myopic astigmatism and for retarding myopic progression in children compared to children wearing single-vision spectacles. Long term changes to other corneal parameters such as posterior cornea curvatures, topographical corneal thickness, corneal hysteresis, corneal resistance factor, with and without ortho-k lens wear will also be investigated.

Conditions

• Myopia
• Astigmatism

Interventions

Type	Name	Description
DEVICE	Toric Orthokeratology lenses	Children wearing toric orthokeratology at night for correcting astigmatism and myopia will be the study group
DEVICE	Single-vision spectacles	Children wearing single-vision spectacles in the daytime for correcting the refractive errors will serve as the control group

Timeline

• Start date: 2008-05-01
• Primary completion: 2012-07-01
• Completion: 2012-12-01
• First posted: 2009-09-17
• Last updated: 2016-02-22

Locations

1 site across 1 country: China