NCT00978133

Study of DERMABOND ProPen in Closure of Colectomy Wounds

Prospective Randomized Study to Evaluate the Use of DERMABOND ProPen (2-octylcyanoacrylate) in the Closure of Abdominal Wounds Versus Closure With Skin Staples in Patients Undergoing Elective Colectomy.

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 74 (actual)
• Sponsor: Singapore General Hospital · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Accepted

Summary

2-octylcyanoacrylate (2-OCA) has been used extensively in clinical practice in trauma, plastic surgery, orthopaedic surgery, emergency medicine and paediatrics. Most studies on 2-OCA to date have focused on closure of short wounds, and only one has included closure of abdominal wounds in the context of general surgery. Here, the investigators will look at the results of closure of abdominal wounds in patients undergoing elective colectomies with 2-OCA, which is commercially available to us, versus closure with skin staples, which is the current standard technique of skin closure employed in the Department of Colorectal Surgery, Singapore General Hospital. The primary objective was to measure effectiveness of 2-OCA in 2 respects - the adequacy of wound healing and cosmesis, and the incidence of superficial wound infection.

Conditions

• Wound

Interventions

Type	Name	Description
PROCEDURE	Dermabond ProPen (2-octylcyanoacrylate)	Application of 2 layers of Dermabond to abdominal wounds after closure of deep layers
PROCEDURE	Skin closure with skin staples	Skin closure with skin staples

Timeline

• Start date: 2006-05-01
• Primary completion: 2007-05-01
• Completion: 2007-05-01
• First posted: 2009-09-16
• Last updated: 2018-04-18

Locations

1 site across 1 country: Singapore