Trials / Completed
CompletedNCT00976196
Platelet Hyperreactivity Project
Platelet Hyperreactivity Project: A System Biology Approach of High On-treatment Platelet Reactivity in Aspirin-treated Cardiovascular Patients
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 110 (actual)
- Sponsor
- Pierre Fontana · Academic / Other
- Sex
- All
- Age
- 18 Years – 99 Years
- Healthy volunteers
- Not accepted
Summary
The PHP study aims to delineate gene products involved in high on-treatment platelet reactivity in aspirin-treated cardiovascular patients.
Detailed description
The PHP study aims to delineate gene products involved in high on-treatment platelet reactivity in aspirin-treated cardiovascular patients using a system biology approach that include proteomics analysis of selected platelet sub-fractions in patients displaying extreme phenotype. Main objective: * to characterize the proteome profile of platelet hyperreactivity in aspirin-treated cardiovascular patients Secondary objectives: * to characterize the platelet hyperreactivity phenotype in cardiovascular patients treated with aspirin * to determine genetic polymorphisms associated with platelet hyperreactivity
Conditions
Timeline
- Start date
- 2009-01-01
- Primary completion
- 2010-01-01
- Completion
- 2010-01-01
- First posted
- 2009-09-14
- Last updated
- 2015-12-02
Locations
1 site across 1 country: Switzerland
Source: ClinicalTrials.gov record NCT00976196. Inclusion in this directory is not an endorsement.