NCT00975910

Effect of Lidocaine in Antiarrhythmic Dosage on Postoperative Cognitive Dysfunction in Supratentorial Craniotomy Dysfunction in Supratentorial Craniotomy

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Capital Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate the effect of lidocaine in antiarrhythmic dosage on postoperative cognitive dysfunction in supratentorial craniotomy.

Conditions

• Supratentorial Craniotomy Dysfunction

Interventions

Type	Name	Description
DRUG	lidocaine	Lidocaine arm: lidocaine (2%) as an intravenous bolus (1.5 mg/kg) during induction followed by an intravenous infusion (2 mg. kg(-1).h(-1)) after induction until at the end of surgery
DRUG	saline	Saline arm: infused at the same rate as lidocaine

Timeline

• Start date: 2009-09-01
• Primary completion: 2012-05-01
• Completion: 2012-12-01
• First posted: 2009-09-14
• Last updated: 2013-05-22

Locations

1 site across 1 country: China