Clinical Trials Directory

Trials / Terminated

TerminatedNCT00975806

Study of Lenalidomide in Combination With Sunitinib to Evaluate the Safety and Efficacy in Patients With Renal Cell Carcinoma

A Phase 1/2, Multicenter, Open-Label, Dose-Escalation Study to Evaluate the Safety and Efficacy of Lenalidomide in Combination With Sunitinib in Subjects With Advanced or Metastatic Renal Cell Carcinoma

Status
Terminated
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
16 (actual)
Sponsor
Celgene · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study was to determine the maximum tolerated dose, safety, and effectiveness of lenalidomide (CC-5013) administered in combination with sunitinib as treatment for patients with renal cell carcinoma.

Conditions

Interventions

TypeNameDescription
DRUGLenalidomideLenalidomide MTD mg by mouth (PO) daily for Days 1- 21 in combination
DRUGSunitinibSunitinib 37.5 mg PO daily on days 1-21 of each 21-day cycle in Cohort A or on days 1-14 in Cohorts F and G

Timeline

Start date
2009-09-01
Primary completion
2011-10-01
Completion
2011-10-01
First posted
2009-09-11
Last updated
2019-11-25
Results posted
2014-12-29

Locations

3 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00975806. Inclusion in this directory is not an endorsement.